RESEARCH NEWS
FROM HHMI

MicroRNAs Intimately Involved in Cancer
(06.09.05)
HHMI investigators have established that tiny RNAs provide a novel genetic route to the initiation of some forms of cancer.

Genetic Tool Reaps Rich Harvest
(04.08.05)
In one fell swoop, scientists have increased from dozens to hundreds the number of known genes that control crucial steps in the development of many organisms from fruit flies to humans.

New RNA Libraries Can Inactivate Human Genes Selectively
(03.25.04)
Researchers have generated large RNA libraries that can be used to turn off individual human and mouse genes to study their function.

Researchers Adapt RNAi to Study Gene Function on a Large Scale
(02.06.04)
HHMI researchers characterized the role in growth and viability of nearly all the genes in the genome of the fruit fly.

Paralyzed Worms Add Pieces to the Puzzle of RNA Interference
(09.15.00)
HHMI researchers pinpoint several genes involved in RNA interference.

HHMI SCIENTISTS AND RNAi

David Bartel

Brenda Bass

Stephen Elledge

H. Robert Horvitz

Scott Lowe

Craig Mello

Norbert Perrimon

FROM THE HHMI BULLETIN

A World Apart
A group of scientists with mammoth imaginations and the best biotech tools is piecing together a view of a prehistoric world where RNA ruled.

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HHMI Bulletin: August 2010

Cover Story: Gut Reaction
The vibrant ecosystem inside the human gut does more than just digest food.

Two Roads to an End
Though separated by an ocean, Christopher Plowe and Abdoulaye Djimdé are bound by their determination to stop malaria's global toll.

Into the Third Dimension
Where 2-D cell cultures fall flat, scientists are adding another dimension to keep cells happy.

Master of Regeneration
Once a high school biology oddity, planarians are moving into the spotlight to reveal secrets of self-renewal.